Brain-Derived Neurotrophic Factor—Major Depressive Disorder and Suicide
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چکیده
منابع مشابه
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Background: Obsessive-Compulsive Disorder (OCD) is a serious neuropsychiatric disorder. The clinical prominence of the OCD symptoms dimensions and Brain-Derived Neurotrophic Factor (BDNF) Val66Met polymorphism are of significant importance. Objectives: The present study aimed to investigate the symptom dimensions and BDNF val66Met polymorphism genotype in Iranian patients with OCD. Materia...
متن کاملBrain-derived neurotrophic factor: role in depression and suicide
Depression and suicidal behavior have recently been shown to be associated with disturbances in structural and synaptic plasticity. Brain-derived neurotrophic factor (BDNF), one of the major neurotrophic factors, plays an important role in the maintenance and survival of neurons and in synaptic plasticity. Several lines of evidence suggest that BDNF is involved in depression, such that the expr...
متن کاملBrain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder.
OBJECTIVE The subgenual anterior cingulate cortex is implicated in the pathology and treatment response of major depressive disorder. Low levels of brain-derived neurotrophic factor (BDNF) and reduced markers for GABA function, including in the amygdala, are reported in major depression, but their contribution to subgenual anterior cingulate cortex dysfunction is not known. METHOD Using polym...
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ژورنال
عنوان ژورنال: OALib
سال: 2019
ISSN: 2333-9721,2333-9705
DOI: 10.4236/oalib.1105106